Review



adipor2 protein expression  (Cusabio)


Bioz Verified Symbol Cusabio is a verified supplier
Bioz Manufacturer Symbol Cusabio manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 92
      Buy from Supplier

    Structured Review

    Cusabio adipor2 protein expression
    Fig. 4 | <t>AdipoR2</t> deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.
    Adipor2 Protein Expression, supplied by Cusabio, used in various techniques. Bioz Stars score: 92/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/adipor2 protein expression/product/Cusabio
    Average 92 stars, based on 4 article reviews
    adipor2 protein expression - by Bioz Stars, 2026-03
    92/100 stars

    Images

    1) Product Images from "Selectively targeting the AdipoR2-CaM-CaMKII-NOS3 axis by SCM-198 as a rapid-acting therapy for advanced acute liver failure."

    Article Title: Selectively targeting the AdipoR2-CaM-CaMKII-NOS3 axis by SCM-198 as a rapid-acting therapy for advanced acute liver failure.

    Journal: Nature communications

    doi: 10.1038/s41467-024-55295-7

    Fig. 4 | AdipoR2 deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.
    Figure Legend Snippet: Fig. 4 | AdipoR2 deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.

    Techniques Used: Staining

    Fig. 5 | SCM-198 regulates NO production through NOS3. a Detection of NO with DAF-FM DA (green) in control or SCM-198 treated AML12 cells. Scale bar, 20 µm. b NO content of the AML12 cells transfected with Adipor2 siRNA or negative control siRNA. Cells were treated with DMSO or SCM-198 for 24 h after H2O2 exposure. c NO content of the TAA/APAP-induced ALF mouse liver tissues measured at 48 hpi. Injured mice were treated with saline or SCM-198 at 24 hpi (in c, d, f, g, i–r). d NO content of WT and Adipor2-/- liver tissues, after TAA/APAP-induced ALF, measured at 48 hpi, normalized to the saline-treated group. e NO content of AML12 cells, with or without L-NAME. f Quantification of necrosis on liver sections of WT and Nos3-/-
    Figure Legend Snippet: Fig. 5 | SCM-198 regulates NO production through NOS3. a Detection of NO with DAF-FM DA (green) in control or SCM-198 treated AML12 cells. Scale bar, 20 µm. b NO content of the AML12 cells transfected with Adipor2 siRNA or negative control siRNA. Cells were treated with DMSO or SCM-198 for 24 h after H2O2 exposure. c NO content of the TAA/APAP-induced ALF mouse liver tissues measured at 48 hpi. Injured mice were treated with saline or SCM-198 at 24 hpi (in c, d, f, g, i–r). d NO content of WT and Adipor2-/- liver tissues, after TAA/APAP-induced ALF, measured at 48 hpi, normalized to the saline-treated group. e NO content of AML12 cells, with or without L-NAME. f Quantification of necrosis on liver sections of WT and Nos3-/-

    Techniques Used: Control, Transfection, Negative Control, Saline



    Similar Products

    adipor2 protein expression  (Cusabio)
    92
    Cusabio adipor2 protein expression
    Fig. 4 | <t>AdipoR2</t> deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.
    Adipor2 Protein Expression, supplied by Cusabio, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/adipor2 protein expression/product/Cusabio
    Average 92 stars, based on 1 article reviews
    adipor2 protein expression - by Bioz Stars, 2026-03
    92/100 stars
    		  Buy from Supplier
    adipor2 protein expression  (Human Protein Atlas)
    90
    Human Protein Atlas adipor2 protein expression
    Fig. 4 | <t>AdipoR2</t> deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.
    Adipor2 Protein Expression, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/adipor2 protein expression/product/Human Protein Atlas
    Average 90 stars, based on 1 article reviews
    adipor2 protein expression - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Fig. 4 | AdipoR2 deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.

    Journal: Nature communications

    Article Title: Selectively targeting the AdipoR2-CaM-CaMKII-NOS3 axis by SCM-198 as a rapid-acting therapy for advanced acute liver failure.

    doi: 10.1038/s41467-024-55295-7

    Figure Lengend Snippet: Fig. 4 | AdipoR2 deficiency abolishes the protective effect of SCM-198 on ALF models. a Representative photograph of WT and Adipor2-/- mouse livers (48 hpi). SCM-198 was given at 24 hpi (in a–f). Black arrowheads indicate sites of severe lesions. Scale bars, 5 mm. b HE staining and quantification analysis on WT and Adipor2-/- mouse liver sections, 48 hpi. Scale bars, 100 μm. c Serum levels of ALT and AST, measured at 48 hpi in WT and Adipor2-/- TAA/APAP-intoxicated mice. d Quantification of GSH in liver tissues of WT and Adipor2-/- mice, 48 hpi.

    Article Snippet: ADIPOR2 protein expression and purification His-tagged ADIPOR2 was expressed in suspension HEK293T cells by Cusabio (Wuhan, China).

    Techniques: Staining

    Fig. 5 | SCM-198 regulates NO production through NOS3. a Detection of NO with DAF-FM DA (green) in control or SCM-198 treated AML12 cells. Scale bar, 20 µm. b NO content of the AML12 cells transfected with Adipor2 siRNA or negative control siRNA. Cells were treated with DMSO or SCM-198 for 24 h after H2O2 exposure. c NO content of the TAA/APAP-induced ALF mouse liver tissues measured at 48 hpi. Injured mice were treated with saline or SCM-198 at 24 hpi (in c, d, f, g, i–r). d NO content of WT and Adipor2-/- liver tissues, after TAA/APAP-induced ALF, measured at 48 hpi, normalized to the saline-treated group. e NO content of AML12 cells, with or without L-NAME. f Quantification of necrosis on liver sections of WT and Nos3-/-

    Journal: Nature communications

    Article Title: Selectively targeting the AdipoR2-CaM-CaMKII-NOS3 axis by SCM-198 as a rapid-acting therapy for advanced acute liver failure.

    doi: 10.1038/s41467-024-55295-7

    Figure Lengend Snippet: Fig. 5 | SCM-198 regulates NO production through NOS3. a Detection of NO with DAF-FM DA (green) in control or SCM-198 treated AML12 cells. Scale bar, 20 µm. b NO content of the AML12 cells transfected with Adipor2 siRNA or negative control siRNA. Cells were treated with DMSO or SCM-198 for 24 h after H2O2 exposure. c NO content of the TAA/APAP-induced ALF mouse liver tissues measured at 48 hpi. Injured mice were treated with saline or SCM-198 at 24 hpi (in c, d, f, g, i–r). d NO content of WT and Adipor2-/- liver tissues, after TAA/APAP-induced ALF, measured at 48 hpi, normalized to the saline-treated group. e NO content of AML12 cells, with or without L-NAME. f Quantification of necrosis on liver sections of WT and Nos3-/-

    Article Snippet: ADIPOR2 protein expression and purification His-tagged ADIPOR2 was expressed in suspension HEK293T cells by Cusabio (Wuhan, China).

    Techniques: Control, Transfection, Negative Control, Saline